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anti-DPYSL3 antibody product blog

Posted on 2015-10-01 12:33:04 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-Dpysl3 antibody; Dpysl3;
The DPYSL3 dpysl3 (Catalog #MBS2525726) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DPYSL3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s DPYSL3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
WB: 1:200-1:1000
IHC: 1:25-1:100. Researchers should empirically determine the suitability of the DPYSL3 dpysl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The DPYSL3 dpysl3 product has the following accession number(s) (GI #308818200) (NCBI Accession #NP_001184223.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the DPYSL3 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Human fetal brain tissue using DPYSL3 Polyclonal Antibody at dilution of 1:250)
Western Blot (WB) DPYSL3.

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human brain using DPYSL3 Polyclonal Antibody at dilution of 1:20)
Immunohistochemistry (IHC) DPYSL3.

Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. Developing neurons in the adult hippocampus of mammals, known as the dentate gyrus, express CRMP-4. Rodent neocortical neurons express CRMP-4 in the perikaryon, in neurites and at growth cones.

Immunogen: Synthetic peptide of human DPYSL3
Calculated Molecular Weight: 62kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DPYSL3 are readily searchable from our website. Different antibodies against the same target such as DPYSL3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. DPYSL3 also interacts with the following gene(s): CDK5, CRMP1, DPYSL2, DPYSL4, DPYSL5, PLXNA1, PLXNA3, PLXNA4, SEMA3A.
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