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anti-DR3 antibody product blog

Posted on 2015-11-11 01:40:20 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; DR3; anti-DR3 antibody;
The DR3 tnfrsf25 (Catalog #MBS221574) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s DR3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western Blotting: Minimum Dilution: 1/500; Maximum Dilution: 1/1000. Researchers should empirically determine the suitability of the DR3 tnfrsf25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The DR3 tnfrsf25 product has the following accession number(s) (GI #89142745) (NCBI Accession #NP_001034753.1) (Uniprot Accession #Q93038). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the RABBIT ANTI HUMAN DR3 (N-TERMINAL) with the following immunoassay(s):
Testing Data #1 (Western blot analysis of whole cell lysate from Jurkat cells probed with Rabbit anti Human DR3 (MBS221574))
Testing Data #1 DR3.

MBS221574 recognises a 59kD apoptosis related protein designated DR3 (death receptor-3).DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95). The ligand for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-KB activation.

Perservative Stabilisers: 0.02% Sodium Azide. Immunogen: Peptide sequence QGGTRSPRCDCAGDFH from amino terminus of human DR3
Buffer Solution: Phosphate buffered saline
Antiserum Preparation: Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Target Species: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DR3 are readily searchable from our website. Different antibodies against the same target such as DR3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Embryonic Tissue, Eye, Heart, Intestine, Lung, Skin, Spleen, Thymus tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Disease Models, Animal, Inflammation, Necrosis, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases, Prostatic Neoplasms, Respiratory Tract Diseases are some of the diseases may be linked to RABBIT ANTI HUMAN DR3 (N-TERMINAL).
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