anti-DRAXIN antibody product blog
Tags: Antibody; Polyclonal Antibody; NEUCRIN; anti-DRAXIN antibody; DRAXIN;
The NEUCRIN draxin (Catalog #MBS9414066) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NEUCRIN Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NEUCRIN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the NEUCRIN draxin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The NEUCRIN draxin product has the following accession number(s) (GI #209954741) (NCBI Accession #BAG80561). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NEUCRIN Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of Neucrin in rat cerebellum tissue lysate with Neucrin antibody at 1 ug/mL.)
Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures. It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin. Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures. Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.
Immunogen Type: Peptide
Immunogen Description: Raised against a 17 amino acid peptide near the carboxy terminus of human Neucrin. Target Name: NEUCRIN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NEUCRIN are readily searchable from our website. Different antibodies against the same target such as NEUCRIN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.