anti-DRD2 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-DRD2 antibody; DRD2; DRD2 / Dopamine Receptor D2;
The DRD2 drd2 (Catalog #MBS244811) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human DRD2 / Dopamine Receptor D2 reacts with Chimpanzee, Gorilla, HumanPredicted Reactivity: Gibbon, Monkey, Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s DRD2 / Dopamine Receptor D2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (5 - 10 ug/ml). Researchers should empirically determine the suitability of the DRD2 drd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DRD2 drd2 product has the following accession number(s) (GI #4503385) (NCBI Accession #NP_000786.1) (Uniprot Accession #P14416). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human DRD2 / Dopamine Receptor D2 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-DRD2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson\'s disease. Three alternatively spliced isoforms have been identified.
Target Species: Human
Immunogen Description: Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human DRD2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Marmoset (100%); Gibbon, Monkey, Rabbit (95%); Dog, Bovine, Panda, Horse, Pig (89%). Immunogen Type: Synthetic peptide
Immunogen: DRD2 / Dopamine Receptor D2 antibody was raised against synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human DRD2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Marmoset (100%); Gibbon, Monkey, Rabbit (95%); Dog, Bovine, Panda, Horse, Pig (89%); Mouse, Rat, Ferret, Bat, Hamster, Elephant (84%).
Antigen Modification: Cytoplasmic Domain. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DRD2 are readily searchable from our website. Different antibodies against the same target such as DRD2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.