|The DUSP22 dusp22 (Catalog #MBS9413953) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DUSP22 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s DUSP22 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).
Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the DUSP22 dusp22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DUSP22 dusp22 product has the following accession number(s) (GI #557440816) (NCBI Accession #NP_001273484.1) (Uniprot Accession #Q9NRW4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the DUSP22 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid tissue using at dilution 1/60.)
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
Immunogen Type: Recombinant Protein
Immunogen Description: Full length fusion protein. Target Name: DUSP22. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DUSP22 are readily searchable from our website. Different antibodies against the same target such as DUSP22 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. DUSP22 also interacts with the following gene(s): DUSP23, MAPK8, STAT3. Adenocarcinoma, Bacterial Infections, Breast Neoplasms, Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms, Lung Neoplasms, Lymphoma, Neoplasm Metastasis, Nervous System Diseases are some of the diseases may be linked to DUSP22 Antibody. Blood, Brain, Liver, Lymph, Lymph Node, Skin, Testis, Thymus, Thyroid, Vascular tissues are correlated with this protein.