anti-EBP antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-EBP antibody; EBP;
The EBP ebp (Catalog #MBS9201805) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EBP Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s EBP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the EBP ebp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EBP ebp product has the following accession number(s) (GI #5729810) (NCBI Accession #NP_006570.1) (Uniprot Accession #Q15125). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the EBP Antibody (C-term) with the following immunoassay(s):
Western Blot (WB) (EBP Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the EBP antibody detected the EBP protein (arrow).)
The protein encoded by this gene is an integral membrane
protein of the endoplasmic reticulum. It is a high affinity binding
protein for the antiischemic phenylalkylamine Ca2+ antagonist
[3H]emopamil and the photoaffinity label [3H]azidopamil. It is
similar to sigma receptors and may be a member of a superfamily of
high affinity drug-binding proteins in the endoplasmic reticulum of
different tissues. This protein shares structural features with
bacterial and eukaryontic drug transporting proteins. It has four
putative transmembrane segments and contains two conserved
glutamate residues which may be involved in the transport of
cationic amphiphilics. Another prominent feature of this protein is
its high content of aromatic amino acid residues (>23%) in its
transmembrane segments. These aromatic amino acid residues have
been suggested to be involved in the drug transport by the
P-glycoprotein. Mutations in this gene cause Chondrodysplasia
punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EBP are readily searchable from our website. Different antibodies against the same target such as EBP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Connective Tissue, Heart, Kidney, Liver, Lung, Muscle tissues are correlated with this protein.