|The ECE2 ece2 (Catalog #MBS416221) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ECE2 Antibody reacts with Human, Rat. Predicted: Mouse. and may cross-react with other species as described in the data sheet. MyBioSource\'s ECE2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the ECE2 ece2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ECE2 ece2 product has the following accession number(s) (GI #153945836) (NCBI Accession #NP_001093591.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-ECE2 Antibody with the following immunoassay(s):
This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide. Immunogen: Rabbit polyclonal ECE2 (1) antibody was raised against a recombinate human ECE2 protein 23-252 aa (BC005835). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ECE2 are readily searchable from our website. Different antibodies against the same target such as ECE2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adrenal Gland, Brain, Embryonic Tissue, Liver, Lung, Muscle, Ovary, Skin tissues are correlated with this protein. Brain Diseases, Hypertension, Inflammation, Lung Diseases are some of the diseases may be linked to Anti-ECE2 Antibody. ECE2 also interacts with the following gene(s): EDN1, EDN2, EDN3, EDNRA, EDNRB, TP53.