anti-EGFR antibody product blog
Tags: Antibody; anti-EGFR antibody; EGFR; Polyclonal Antibody;
The EGFR egfr (Catalog #MBS631090) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EGFR, phosphorylated (Tyr1016) (Epidermal Growth Factor Receptor, Receptor Tyrosine-protein Kinase ErbB-1, Proto-oncogene c-ErbB-1, ERBB1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s EGFR can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Gel Shift Assay (GS/EMSA).Suitable for use in ELISA and Dot Blot.
Dilution: ELISA: 1:1,000
Dot Blot: 1:500. Researchers should empirically determine the suitability of the EGFR egfr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EGFR egfr product has the following accession number(s) (GI #29725609) (NCBI Accession #NP_005219.2) (Uniprot Accession #P00533). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the EGFR, phosphorylated (Tyr1016) (Epidermal Growth Factor Receptor, Receptor Tyrosine-protein Kinase ErbB-1, Proto-oncogene c-ErbB-1, ERBB1) with the following immunoassay(s):
Dot Blot (DB) (Dot blot analysis of anti-EGFR B1 Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.)
Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. It is involved in the control of cell growth and differentiation.
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1016 of human EGFR (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EGFR are readily searchable from our website. Different antibodies against the same target such as EGFR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Kidney Diseases, Lung Diseases, Lung Neoplasms, Neoplasms are some of the diseases may be linked to EGFR, phosphorylated (Tyr1016) (Epidermal Growth Factor Receptor, Receptor Tyrosine-protein Kinase ErbB-1, Proto-oncogene c-ErbB-1, ERBB1).