anti-eIF4B antibody product blog
Tags: Antibody; Polyclonal Antibody; EIF4B; anti-Eif4b antibody;
The eIF4B eif4b (Catalog #MBS9406273) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The eIF4B (Ab-422) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s eIF4B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the eIF4B eif4b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The eIF4B eif4b product has the following accession number(s) (GI #50053795) (NCBI Accession #NP_001408.2) (Uniprot Accession #P23588). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the eIF4B (Ab-422) Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from 3T3 and HL60 cells using eIF4B(Ab-422) Antibody.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using eIF4B(Ab-422) Antibody (left) or the same antibody preincubated with blocking peptide(right).)
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5\'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-An and EIF4-F.
Immunogen Type: Peptide-KLH
Immunogen Description: Peptide sequence around aa.420~424 (T-G-S-E-S) derived from Human eIF4B. Target Name: eIF4B. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing eIF4B are readily searchable from our website. Different antibodies against the same target such as eIF4B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. eIF4B also interacts with the following gene(s): EIF4A1, EIF4E, EIF4G1, EIF4G2, PABPC1, RPS6KB1. Blood, Brain, Kidney, Liver, Lung, Mouth, Muscle, Prostate, Thymus, Vascular tissues are correlated with this protein. Cardiovascular Diseases, Cell Transformation, Neoplastic, Disease Models, Animal, Fibrosis, Kidney Diseases, Necrosis, Neoplasm Metastasis, Neoplasms, Experimental, Prostatic Neoplasms, Weight Loss are some of the diseases may be linked to eIF4B (Ab-422) Antibody.