anti-EP-CAM antibody product blog
Tags: Antibody; Polyclonal Antibody; Ep-CAM; Epithelial Cell Adhesion Molecule, Ep-CAM; anti-Ep-CAM antibody;
The EP-CAM epcam (Catalog #MBS355089) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Anti- Epithelial cell adhesion molecule, EP-CAM reacts with Human, mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Epithelial cell adhesion molecule, EP-CAM can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS).Western Blot (1:1000-2000)
Immunohistochemistry (1:200-500)
Immunocytochemistry (1:100-200)
Flow Cytometry (1:100-200)
Other applications have not been tested.
The optimal dilutions should be determined by end user. Researchers should empirically determine the suitability of the EP-CAM epcam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EP-CAM epcam product has the following accession number(s) (GI #15928632) (NCBI Accession #AAH14785.1) (Uniprot Accession #P16422). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Monoclonal Anti- Epithelial cell adhesion molecule, EP-CAM with the following immunoassay(s):
Western Blot (WB)
Immunohistochemistry (IHC)
Epithelial cell adhesion molecule (Ep-CAM) is a pan-epithelial differentiation antigen. [1]It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signalling and polarity. It has been used as an immunotherapeutic target in the treatment of gastrointestinal, urological and other carcinomas. [2]It is expressed in undifferentiated pluripotent stem cells. [3] and it is being used as a target for immunotherapy treatment of human carcinomas.
Immunogen: Recombinant EP-CAM protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EP-CAM are readily searchable from our website. Different antibodies against the same target such as EP-CAM may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. EP-CAM also interacts with the following gene(s): CD44, CDH1, CLDN7, MSH2, TSPAN8. Ascites, Blood, Intestine, Kidney, Liver, Lung, Lymph Node, Prostate, Stomach, Vascular tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Carcinoma, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms, Experimental are some of the diseases may be linked to Monoclonal Anti- Epithelial cell adhesion molecule, EP-CAM.