anti-EP300 antibody product blog
Tags: Antibody; EP300; anti-EP300 antibody; Polyclonal Antibody;
The EP300 ep300 (Catalog #MBS9412255) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EP300 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s EP300 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the EP300 ep300 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EP300 ep300 product has the following accession number(s) (GI #50345997) (NCBI Accession #NP_001420.2) (Uniprot Accession #Q09472). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the EP300 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/20.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.)
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Immunogen Type: Peptide
Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human E1A binding protein p300. Target Name: EP300. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EP300 are readily searchable from our website. Different antibodies against the same target such as EP300 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. EP300 also interacts with the following gene(s): CARM1, CREB1, ESR1, HIF1A, MYB, MYOD1, NCOA3, RELA, SMAD3, TP53. Breast Neoplasms, Cardiovascular Diseases, Cell Transformation, Neoplastic, Colorectal Neoplasms, Inflammation, Lung Diseases, Lung Neoplasms, Necrosis, Neoplasms, Experimental, Rubinstein-Taybi Syndrome are some of the diseases may be linked to EP300 Antibody. Blood, Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Nerve tissues are correlated with this protein.