anti-EPAC1 antibody product blog
Tags: Antibody; Polyclonal Antibody; EPAC1; anti-EPAC1 antibody;
The EPAC1 rapgef3 (Catalog #MBS540635) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Epac1 Antibody reacts with Horse, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s EPAC1 can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB).Confocal Microscopy: 1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500. Researchers should empirically determine the suitability of the EPAC1 rapgef3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EPAC1 rapgef3 product has the following accession number(s) (GI #4079649) (NCBI Accession #AAD12740.1) (Uniprot Accession #O95398). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Epac1 Antibody with the following immunoassay(s):
Western Blot (WB)
Affinity Purified Rap Guanine Nucleotide Exchange Factor 3 Antibody Mid-Region
Guanine nucleotide exchange factor for RAP1A and RAP2A small GTPases that are activated by binding cAMP.
Immunogen: Synthetic peptide corresponding to amino acids 526-541 of Epac1 protein, peptide was covalently modified.
Sequence: DHSVLTLQLQLPVTASVR
Expression: Widely expressed with highest levels in kidney, heart, thyroid and brain. Determinant: Mid-Region
Molecular Function: cAMP-binding; Nucleotide-binding
Structure: Interacts with PDE3B
Subcellular Location: Endomembrane system. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EPAC1 are readily searchable from our website. Different antibodies against the same target such as EPAC1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. EPAC1 also interacts with the following gene(s): ABCC8, PDE3B, PDE4A, RAP1A, RAP1B, RAP1GAP. Cardiovascular Diseases, Edema, Fibrosis, Heart Diseases, Heart Failure, Hypertrophy, Inflammation, Lung Diseases, Necrosis, Vascular Diseases are some of the diseases may be linked to Epac1 Antibody. Blood, Brain, Heart, Kidney, Lung, Muscle, Pancreas, Prostate, Umbilical Cord, Vascular tissues are correlated with this protein.