|The ERBB4 erbb4 (Catalog #MBS247531) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human ERBB4 / HER4 reacts with Bat, Gibbon, Chicken, Dog, Horse, Human, Monkey, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ERBB4 / HER4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (16 ug/ml). Researchers should empirically determine the suitability of the ERBB4 erbb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ERBB4 erbb4 product has the following accession number(s) (GI #4885215) (NCBI Accession #NP_005226.1) (Uniprot Accession #Q15303). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human ERBB4 / HER4 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-ERBB4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
ERBB-4 receptor tyrosine kinase is activated by neuregulins, nrg- 2, nrg-3, heparin-binding egf-like growth factor, betacellulin and ntak to regulate cell proliferation and differentiation. Several isoforms of the ERBB-4 receptor tyrosine kinase have been identified and differ functionally in their response to phorbol ester: they represent cleavable and noncleavable forms of the receptor. These isoforms are differentially expressed in tissues.
Target Species: Human
Immunogen Description: Synthetic 20 amino acid peptide from internal region of human ERBB4. Percent identity with other species by BLAST analysis: Human, Gibbon, Marmoset, Mouse, Rat, Panda, Dog, Bat, Horse, Pig, Opossum, Turkey, Chicken, Platypus (100%). Immunogen Type: Synthetic peptide
Immunogen: ERBB4 / HER4 antibody was raised against synthetic 20 amino acid peptide from internal region of human ERBB4. Percent identity with other species by BLAST analysis: Human, Gibbon, Marmoset, Mouse, Rat, Panda, Dog, Bat, Horse, Pig, Opossum, Turkey, Chicken, Platypus (100%).
Antigen Modification: Internal. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ERBB4 are readily searchable from our website. Different antibodies against the same target such as ERBB4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Embryonic Tissue, Heart, Kidney, Lung, Mammary Gland, Muscle, Ovary, Pancreas, Uterus tissues are correlated with this protein.