|The ERC1 erc1 (Catalog #MBS6001668) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ERC1 (ELKS, KIAA1081, RAB6IP2, ELKS/Rab6-interacting/CAST Family Member 1, Rab6-interacting Protein 2) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ERC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Suitable for use in Western Blot. Researchers should empirically determine the suitability of the ERC1 erc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ERC1 erc1 product has the following accession number(s) (GI #38045898) (NCBI Accession #NP_829884.1) (Uniprot Accession #Q8IUD2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MPKQVVWHGH WPAALSKQVA QIPPTWTFSS GAAPATLSHW VCDSPLHLSI LHHFPSRKTD GRKPSVTLLL RRSISGTDII CLVSVNSKES S.
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Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. The protein is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Five transcript variants encoding different isoforms have been found for this gene.
Immunogen: Full length human ERC1, aa1-91 (AAH05065.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ERC1 are readily searchable from our website. Different antibodies against the same target such as ERC1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Breast Neoplasms, Carcinoma, Inflammation, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Necrosis, Neoplasms, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to ERC1 (ELKS, KIAA1081, RAB6IP2, ELKS/Rab6-interacting/CAST Family Member 1, Rab6-interacting Protein 2). Blood, Bone, Brain, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Thyroid tissues are correlated with this protein.