anti-ESR1 antibody product blog
Tags: Antibody; Polyclonal Antibody; ESR1; anti-ESR1 antibody;
The ESR1 esr1 (Catalog #MBS153681) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ESR1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ESR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).ESR1 antibody can be used for detection of ESR1 by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the ESR1 esr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ESR1 esr1 product has the following accession number(s) (GI #170295804) (NCBI Accession #NP_001116214) (Uniprot Accession #P03372). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ESR1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of ESR1 in rat brain tissue lysate with ESR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC) (Immunohistochemistry of ESR1 in rat brain tissue with ESR1 antibody at 5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of ESR1 in rat brain tissue with ESR1 antibody at 20 μg/mL.)
ESR1 Antibody: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors (1). Estrogen receptors, including ESR1, also known as ER-alpha and ESR2 (ER-beta), contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ESR1 is a widely expressed nuclear protein and serves as a strong activator of estrogen responsive genes (1,2). Phosphorylation of serines 104 and 106, located in the N-terminal transcription activation function-1 domain (AF-1), plays a large role in regulating ER alpha activity (3).
Conjugate: Unconjugated
Immunogen: ESR1 antibody was raised against an 18 amino acid peptide near the center of human ESR1.
Buffer: ESR1 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ESR1 are readily searchable from our website. Different antibodies against the same target such as ESR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.