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anti-ESR1 antibody product blog

Posted on 2016-01-01 08:42:51 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; ESR1; anti-ESR1 antibody; Estrogen Receptor-alpha;
The ESR1 esr1 (Catalog #MBS9414151) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Estrogen Receptor-alpha (Phospho-Ser102) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Estrogen Receptor-alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the ESR1 esr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The ESR1 esr1 product has the following accession number(s) (GI #62821794) (NCBI Accession #NP_000116.2) (Uniprot Accession #P03372). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Estrogen Receptor-alpha (Phospho-Ser102) Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from HuvEc cells (Lane 2), using Estrogen Receptor-a (Phospho-Ser102) Antibody. The lane on the left is treated with antigen-specific peptide.)
Western Blot (WB) ESR1.

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Estrogen Receptor-a (Phospho-Ser102) antibody (left)or the same antibody preincubated with blocking peptide (right).)
Immunohistochemistry (IHC) ESR1.

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Immunogen Type: Peptide-KLH
Immunogen Description: Peptide sequence around phosphorylation site of Serine102(L-N-S(p)-V-S) derived from Human Estrogen Receptor-a. Modification: Phospho-Ser102
Target Name: Estrogen Receptor-a. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ESR1 are readily searchable from our website. Different antibodies against the same target such as ESR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. ESR1 also interacts with the following gene(s): BRCA1, CREBBP, EP300, HDAC1, NCOA1, NCOA2, NCOA3, NRIP1, SP1, SRC. Brain, Connective Tissue, Heart, Lung, Mammary Gland, Muscle, Ovary, Prostate, Testis, Uterus tissues are correlated with this protein. Adenocarcinoma, Bone Diseases, Metabolic, Carcinoma, Disease Models, Animal, Disease Progression, Female Urogenital Diseases, Infertility, Female, Neoplasm Metastasis, Obesity, Prostatic Neoplasms are some of the diseases may be linked to Estrogen Receptor-alpha (Phospho-Ser102) Antibody.
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