|The ESRRA esrra (Catalog #MBS6004770) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ESRRA (Steroid Hormone Receptor ERR1, Estrogen-related Receptor, alpha, ERR-alpha, Estrogen Receptor-like 1, Nuclear Receptor Subfamily 3 Group B Member 1, NR3B1, ESRL1, ERR1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ESRRA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Suitable for use in Western Blot. Researchers should empirically determine the suitability of the ESRRA esrra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ESRRA esrra product has the following accession number(s) (GI #62205021) (NCBI Accession #AAH92470.1) (Uniprot Accession #P11474). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MSSQVVGIEP LYIKAEPASP DSPKGSSETE TEPPVALAPG PAPTRCLPGH KEEEDGEGAG PGEQGGGKLV LSSLPKRLCL VCGDVASGYH YGVASCEACK AFFKRTIQGS IEYSCPASNE CEITKRRRKA CQACRFTKCL RVGMLKEGVR LDRVRGGRQK YKRRPEVDPL PFPGPFPAGP LAVAGGPRKT AAPVNALVSH LLVVEPEKLY AMPDPAGPDG HLPAVATLCD LFDREIVVTI SWAKSIPGFS SLSLSDQMSV LQSVWMEVLV LGVAQRSLPL QDELAFAEDL VLDEEGARAA GLGELGAALL QLVRRLQALR LEREEYVLLK ALALANSDSV HIEDAEAVEQ LREALHEALL EYEAGRAGPG GGAERRRAGR LLLTLPLLRQ TAGKVLAHFY GVKLEGKVPM HKLFLEMLEA MMD.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.
Immunogen: Full length human ESRRA, aa1-423 (NP_004442.3). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ESRRA are readily searchable from our website. Different antibodies against the same target such as ESRRA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Endometrial Neoplasms, Fatty Liver, Metabolic Diseases, Neoplasms, Nervous System Diseases, Ovarian Neoplasms, Uterine Cervical Neoplasms, Uterine Neoplasms, Weight Loss are some of the diseases may be linked to ESRRA (Steroid Hormone Receptor ERR1, Estrogen-related Receptor, alpha, ERR-alpha, Estrogen Receptor-like 1, Nuclear Receptor Subfamily 3 Group B Member 1, NR3B1, ESRL1, ERR1).