anti-EXOC2 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-EXOC2 antibody; EXOC2;
The EXOC2 exoc2 (Catalog #MBS9128506) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EXOC2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s EXOC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB 1:500 - 1:2000. Researchers should empirically determine the suitability of the EXOC2 exoc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EXOC2 exoc2 product has the following accession number(s) (GI #21361625) (NCBI Accession #NP_060773.3) (Uniprot Accession #Q96KP1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the EXOC2 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using EXOC2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.)
The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human EXOC2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EXOC2 are readily searchable from our website. Different antibodies against the same target such as EXOC2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.