anti-EXOSC1 antibody product blog
Tags: Antibody; Polyclonal Antibody; EXOSC1; anti-EXOSC1 antibody;
The EXOSC1 n/a (Catalog #MBS644731) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The EXOSC1 (CSL4, Exosome Complex Component CSL4, Exosome Component 1, CGI-108, SKI4, Ski4p, hCsl4p, p13) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s EXOSC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF).Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml. Researchers should empirically determine the suitability of the EXOSC1 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EXOSC1 n/a product has the following accession number(s) (GI #62751675) (NCBI Accession #NP_001015529.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MAPPVRYCIP GERLCNLEEG SPGSGTYTRH GYIFSSLAGC LMKSSENGAL PVVSVVRETE SQLLPDVGAI VTCKVSSINS RFAKVHILYV GSMPLKNSFR GTIRKEDVRA TEKDKVEIYK SFRPGDIVLA KVISLGDAQS NYLLTTAENE LGVVVAHSES GIQMVPISWC EMQCPKTHTK EFRKVARVQP EFLQT.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the EXOSC1 (CSL4, Exosome Complex Component CSL4, Exosome Component 1, CGI-108, SKI4, Ski4p, hCsl4p, p13) with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of EXOSC1 expression in transfected 293T cell line by EXOSC1 polyclonal antibody. Lane 1: EXOSC1 transfected lysate (21.56kD). Lane 2: Non-transfected lysate.)
Immunofluorescence (IF) (Immunofluorescence of purified antibody to EXOSC1 on HeLa cell. [antibody concentration 10ug/ml].)
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
Immunogen: Full length human EXOSC1, aa1-196 (AAH22067). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EXOSC1 are readily searchable from our website. Different antibodies against the same target such as EXOSC1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.