|The F11R f11r (Catalog #MBS9401704) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The F11R Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s F11R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100
Immunofluorescence: 1:50 - 1:200. Researchers should empirically determine the suitability of the F11R f11r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The F11R f11r product has the following accession number(s) (GI #8393638) (NCBI Accession #NP_058642.1) (Uniprot Accession #Q9Y624). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the F11R Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of HeLa cell lysate using F11R antibody.)
Immunofluorescence (IF) (Immunofluorescence analysis of HeLa cell using F11R antibody. Blue: DAPI for nuclear staining.)
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5\' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Immunogen Type: Recombinant Protein
Immunogen Description: Recombinant protein of human F11R. Target Name: F11R. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing F11R are readily searchable from our website. Different antibodies against the same target such as F11R may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Breast Neoplasms, Disease Models, Animal, Edema, Heart Diseases, Inflammation, Kidney Diseases, Lung Neoplasms, Necrosis, Neoplasm Invasiveness, Neoplasm Metastasis are some of the diseases may be linked to F11R Antibody.