anti-FAM120A antibody product blog
Tags: Antibody; Polyclonal Antibody; FAM120A; anti-FAM120A antibody;
The FAM120A fam120a (Catalog #MBS9407124) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FAM120A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s FAM120A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the FAM120A fam120a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The FAM120A fam120a product has the following accession number(s) (GI #39652628) (NCBI Accession #NP_055427). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FAM120A Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of FAM120A in SK-N-SH cell lysate with FAM120A antibody at (A) 0.5 and (B) 1 ug/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of FAM120A in rat brain tissue with FAM120A antibody at 2.5 ug/mL.)
FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.
Immunogen Type: Peptide
Immunogen Description: Raised against an 18 amino acid peptide from near the center of human FAM120A. Target Name: FAM120A. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FAM120A are readily searchable from our website. Different antibodies against the same target such as FAM120A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.