|The FBG5 n/a (Catalog #MBS536213) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FBG5 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FBG5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the FBG5 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
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Affinity purified Rabbit polyclonal FBG5 antibody.
Biological Significance: F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: FBG5 antibody was raised in rabbit using residues 163-175 (KKQVLDLEEEGLW) of the human FBG5 protein as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FBG5 are readily searchable from our website. Different antibodies against the same target such as FBG5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.