anti-FERMT3 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-FERMT3 antibody; FERMT3; UNC-112 related protein 2;
The FERMT3 fermt3 (Catalog #MBS626347) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The UNC-112 related protein 2 (fermitin family homolog 3, KIND3, Kindlin-3, MGC10966, MIG-2, MIG2B, MIG2-like, UNC112C,, Unc-112-related protein 2, URP2, URP2SF) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s UNC-112 related protein 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: Peptide ELISA Titer: 1:2000
Western Blot: 1-3ug/ml detects ~75kD band observed in Human Peripheral Blood Mononucleocytes lysates (calculated MW of 75.4kD according to NP_113659.3). Researchers should empirically determine the suitability of the FERMT3 fermt3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FERMT3 fermt3 product has the following accession number(s) (GI #119594606) (Uniprot Accession #Q86UX7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the UNC-112 related protein 2 (fermitin family homolog 3, KIND3, Kindlin-3, MGC10966, MIG-2, MIG2B, MIG2-like, UNC112C,, Unc-112-related protein 2, URP2, URP2SF) with the following immunoassay(s):
Chemiluminescence (U1610-13 (1ug/ml) staining of Human Peripheral Blood Mononucleocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Immunogen: Synthetic peptide corresponding to C-ERARGEELDED, from the C-Terminus of human URP2 (NP_113659.3; NP_848537.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FERMT3 are readily searchable from our website. Different antibodies against the same target such as FERMT3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.