|The FEZ2 fez2 (Catalog #MBS151297) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FEZ2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s FEZ2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF).
FEZ2 antibody can be used for the detection of FEZ2 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunoflourescence starting at 5 mug/mL. For immunofluorescence start at 5 mug/mL. Researchers should empirically determine the suitability of the FEZ2 fez2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FEZ2 fez2 product has the following accession number(s) (GI #110349756) (NCBI Accession #NP_001036013) (Uniprot Accession #Q9UHY8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FEZ2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of FEZ2 in 3T3 cell lysate with FEZ2 antibody at (A) 0.5, and (B) 1 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of human brain tissue using FEZ2 antibody at 5 μg/mL.)
FEZ2 Antibody: Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
Immunogen: FEZ2 antibody was raised against a 15 amino acid synthetic peptide from near the center of human FEZ2.
Buffer: FEZ2 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FEZ2 are readily searchable from our website. Different antibodies against the same target such as FEZ2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.