|The FGFR1 fgfr1 (Catalog #MBS242640) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human FGFR1 reacts with Bat, Gibbon, Bovine, Dog, Gorilla, Horse, Human, Monkey, Orangutan
Predicted Reactivity: Rat, Hamster, Pig (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s FGFR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA).
ELISA (1:32000), IHC-P (4 ug/ml), WB (0.3 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the FGFR1 fgfr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FGFR1 fgfr1 product has the following accession number(s) (GI #291327489) (NCBI Accession #NP_001167534.1) (Uniprot Accession #P11362). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat Polyclonal to Human FGFR1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-FGFR1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.)
Immunohistochemistry (IHC) (Anti-FGFR1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.)
Western Blot (WB) (Antibody (0.3 ug/ml) staining of human breast lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
The fibroblast growth factor receptor 1 belongs to the FGF Receptor subfamily. The full-length protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Ligand binding results in the activation of a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Various isoforms of FGFR1 have been identified that differ in structure and specificity.
Target Species: Human
Immunogen Description: Synthetic peptide CLPRHPAQLANGGLKR from the C-terminus of human FGFR1 (NP_075598.2; NP_056934.2; NP_075593.1; NP_075594.1; NP_075599.1). Immunogen Type: Synthetic peptide
Immunogen: FGFR1 antibody was raised against synthetic peptide CLPRHPAQLANGGLKR from the C-terminus of human FGFR1 (NP_075598.2; NP_056934.2; NP_075593.1; NP_075594.1; NP_075599.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Horse, Platypus (100%); Rat, Hamster, Pig, Opossum (94%); Mouse, Rabbit (88%).
Antigen Modification: C-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FGFR1 are readily searchable from our website. Different antibodies against the same target such as FGFR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.