anti-FKBP1A antibody product blog
Tags: Antibody; Polyclonal Antibody; FKBP1A; anti-FKBP1A antibody; Peptidyl-prolyl cis-trans isomerase FKBP1A;
The FKBP1A fkbp1a (Catalog #MBS715055) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Peptidyl-prolyl cis-trans isomerase FKBP1A polyclonal Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Peptidyl-prolyl cis-trans isomerase FKBP1A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the FKBP1A fkbp1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The FKBP1A fkbp1a product has the following accession number(s) (GI #4503725) (NCBI Accession #NP_000792.1) (Uniprot Accession #P62942). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti-human Peptidyl-prolyl cis-trans isomerase FKBP1A polyclonal Antibody, HRP conjugated with the following immunoassay(s):
Western Blot (WB) (Western blot All lanes: Peptidyl-prolyl cis-trans isomerase FKBP1A antibody at at 2 /mlLane 1: EC109 whole cell lysateLane 2: 293T whole cell lysate SecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size: 12 kDa Observed band size: 22 kDa Additional bands at: 36 kDa. We are unsure as to the identity of these extra band. Why is the actual band size different from the predicted Western blotting is a technique that separates proteins based on size - in general, the smaller the protein the faster it migrates through the gel. However, migration is also affected by other factors and so the actual band size observed may differ from that predicted. Common factors include.. � post-translational modification - e.g. phosphorylation, glycosylation etc which increases the size of the protein � post-translation cleavage - e.g. many proteins are synthesized as pro-proteins, and then cleaved to give the active form, e.g. pro-caspases � splice variants - alternative splicing may create different sized proteins from the same gene � relative charge - the composition of amino acids (charged vs non-charged) multimers - e.g. dimerisation of a protein. This is usually prevented in reducing conditions, although strong interactions can result in the appearance of higher bands.)
May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: HRP.