|The FNIP2 fnip2 (Catalog #MBS150813) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FNIP2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s FNIP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
FNIP2 antibody can be used for detection of FNIP2 by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the FNIP2 fnip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FNIP2 fnip2 product has the following accession number(s) (GI #154689769) (NCBI Accession #NP_065891) (Uniprot Accession #Q9P278). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FNIP2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of FNIP2 in mouse skeletal muscle lysate with FNIP2 antibody at (A) 1 and (B) 2 μg/mL.)
FNIP2 Antibody: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.
Immunogen: FNIP2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human FNIP2.
Buffer: FNIP2 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FNIP2 are readily searchable from our website. Different antibodies against the same target such as FNIP2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. FNIP2 also interacts with the following gene(s): FLCN. Brain, Kidney, Lung, Nerve tissues are correlated with this protein.