|The FOLR2 folr2 (Catalog #MBS6013574) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOLR2, NT (FOLR2, Folate receptor beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s FOLR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the FOLR2 folr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FOLR2 folr2 product has the following accession number(s) (GI #166064054) (NCBI Accession #NP_001107007.1) (Uniprot Accession #P14207). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Immunogen: FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of human FOLR2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FOLR2 are readily searchable from our website. Different antibodies against the same target such as FOLR2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Heart, Intestine, Lung tissues are correlated with this protein. FOLR2 also interacts with the following gene(s): CD163. The following patways have been known to be associated with this gene. Cleft Palate, Congenital Abnormalities, Disease Models, Animal, Fatty Liver, Inflammation, Neoplasms, Nervous System Diseases, Neural Tube Defects, Weight Gain, Weight Loss are some of the diseases may be linked to FOLR2, NT (FOLR2, Folate receptor beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein).