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anti-FOXM1 antibody product blog

Posted on 2015-10-25 11:27:18 by mybiosource_staff
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Tags: Antibody; FOXM1; anti-FOXM1 antibody; Polyclonal Antibody; Forkhead box protein M1;
The FOXM1 foxm1 (Catalog #MBS177412) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FOXM1 Antibody reacts with Human. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. MyBioSource\'s Forkhead box protein M1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western Blot: Concentration: 0.1-0.5mug/ml; Tested Species: Human. Researchers should empirically determine the suitability of the FOXM1 foxm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The FOXM1 foxm1 product has the following accession number(s) (GI #340545543) (NCBI Accession #NP_001230017.1) (Uniprot Accession #Q08050). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-FOXM1 Antibody with the following immunoassay(s):
Western Blot (WB) (Anti- FOXM1 antibody, MBS177412, Western blotting
All lanes: Anti FOXM1 (MBS177412) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: COLO320 Whole Cell Lysate at 40ug
Lane 3: SW620 Whole Cell Lysate at 40ug
Lane 4: SKOV Whole Cell Lysate at 40ug
Lane 5: MCD-7 Whole Cell Lysate at 40ug
Predicted bind size: 84KD
Observed bind size: 84KD )
Western Blot (WB) FOXM1.

Western Blot (WB) (Anti- FOXM1 antibody, MBS177412, Western blotting
All lanes: Anti FOXM1 (MBS177412) at 0.5ug/ml
WB: Recombinant Human FOXM1 Protein 0.5ng
Predicted bind size: 36KD
Observed bind size: 36KD )
Western Blot (WB) FOXM1.

Description: Rabbit IgG polyclonal antibody for Forkhead box protein M1(FOXM1) detection. Tested with WB in Human.
Background: Forkhead box protein M1, also called FOXM1, is a protein that in humans is encoded by the FOXM1 gene. It is mapped to 12p13.33. The protein encoded by this gene is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. FOXM1 gene is now known as a human proto-oncogene. Abnormal upregulation of FOXM1 is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It was hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. What\'s more, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of FOXM1 "brain washes" normal cells to adopt cancer-like epigenome.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen: E.coli-derived human FOXM1 recombinant protein (Position: A411-Q763). Human FOXM1 shares 75% and 76% amino acid (aa) sequences identity with mouse and rat FOXM1, respectively. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FOXM1 are readily searchable from our website. Different antibodies against the same target such as FOXM1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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