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anti-FXR antibody product blog

Posted on 2016-08-11 22:53:22 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; FXR; anti-fxr antibody;
The FXR nr1h4 (Catalog #MBS856404) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FXR Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s FXR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Peptide ELISA titer: 1:1,000-1:5,000
Western blot analysis: 1:200-1:500
Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the FXR nr1h4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The FXR nr1h4 product has the following accession number(s) (GI #142360165) (NCBI Accession #NP_005114.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FXR Antibody with the following immunoassay(s):
Testing Data
Testing Data FXR.

Source Note: Rabbit polyclonal FXR(1) antibody was raised against a 13 amino acid peptide from near the C terminal residues of human FXR protein.
Reactivity Note: Not yet tested in other species. Pathway: nuclear receptor subfamily 1, group H, member 4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FXR are readily searchable from our website. Different antibodies against the same target such as FXR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. FXR also interacts with the following gene(s): ABCB11, ABCB4, CYP7A1, CYP8B1, NR0B2, SLC10A1. Adrenal Gland, Blood, Brain, Connective Tissue, Heart, Intestine, Kidney, Liver, Ovary tissues are correlated with this protein. The following patways have been known to be associated with this gene. Atherosclerosis, Carcinoma, Hepatocellular, Cholestasis, Disease Models, Animal, Fatty Liver, Inflammation, Insulin Resistance, Intestinal Neoplasms, Liver Diseases, Liver Neoplasms are some of the diseases may be linked to FXR Antibody.
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