|The FZD6 fzd6 (Catalog #MBS244363) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human FZD6 / Frizzled 6 reacts with Human
Predicted Reactivity: Gorilla, Orangutan, Gibbon, Monkey, Bovine, Horse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s FZD6 / Frizzled 6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (14 ug/ml). Researchers should empirically determine the suitability of the FZD6 fzd6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FZD6 fzd6 product has the following accession number(s) (GI #34734079) (NCBI Accession #NP_003497.2) (Uniprot Accession #O60353). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human FZD6 / Frizzled 6 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.)
Immunohistochemistry (IHC) (Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.)
FZD6 is a Frizzled Receptor for Wnt signaling proteins involved in patterning during development. Contrary to other Frizzled proteins, FZD6 does not contain a C-terminal PDZ domain-binding motif. FZD6 is widely expressed. The Drosophila homolog activates Dishevelled.
Target Species: Human
Immunogen Description: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human Frizzled-6. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Horse (94%). Immunogen Type: Synthetic peptide
Immunogen: FZD6 / Frizzled 6 antibody was raised against synthetic 17 amino acid peptide from N-terminal extracellular domain of human Frizzled-6. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Horse (94%); Elephant, Pig, Opossum (88%); Panda, Bat, Rabbit (82%).
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FZD6 are readily searchable from our website. Different antibodies against the same target such as FZD6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. FZD6 also interacts with the following gene(s): CTHRC1, DVL1, DVL2, DVL3, FZD5, SFRP1, WNT11, WNT16, WNT3A, WNT4.