|The G g (Catalog #MBS1489467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Rabies virus Glycoprotein G polyclonal Antibody, HRP conjugated reacts with Rabies virus and may cross-react with other species as described in the data sheet. MyBioSource\'s Rabies virus Glycoprotein G can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the G g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The G g product has the following accession number(s) (GI #138301) (NCBI Accession #P03524.1) (Uniprot Accession #P03524). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein G and thereby facilitate rabies virus entry into cells.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: HRP. Immunogen: Recombinant Rabies virus Glycoprotein G protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing G are readily searchable from our website. Different antibodies against the same target such as G may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.