anti-GAB3 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-GAB3 antibody; GAB3;
The GAB3 gab3 (Catalog #MBS6004634) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GAB3, NT (GAB3, GRB2-associated-binding protein 3, GRB2-associated binder 3, Growth factor receptor bound protein 2-associated protein 3) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s GAB3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the GAB3 gab3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GAB3 gab3 product has the following accession number(s) (GI #126091130) (NCBI Accession #NP_001075042.1) (Uniprot Accession #Q8WWW8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GAB3, NT (GAB3, GRB2-associated-binding protein 3, GRB2-associated binder 3, Growth factor receptor bound protein 2-associated protein 3) with the following immunoassay(s):
Western Blot (WB) (GAB3 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the GAB3 antibody detected the GAB3 protein (arrow).)
GAB3 is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen: GAB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human GAB3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GAB3 are readily searchable from our website. Different antibodies against the same target such as GAB3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Eye, Kidney, Thymus, Vascular tissues are correlated with this protein. GAB3 also interacts with the following gene(s): GRB2, PTPN11, SRC.