anti-GAD1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-GAD1 antibody; GAD1;
The GAD1 gad1 (Catalog #MBS2542796) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GAD1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GAD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).ELISA: 1:1000-2000
IHC: 1:25-100
WB: 1:200-1000. Researchers should empirically determine the suitability of the GAD1 gad1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GAD1 gad1 product has the following accession number(s) (GI #114053971). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GAD1 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer using GAD1 Polyclonal Antibody at dilution of 1/20)
Western Blot (WB) (Western Blot analysis of Mouse brain tissue using GAD1 Polyclonal Antibody at dilution of 1/200)
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.�.
Immunogen: Synthetic peptide of human GAD1
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7512 / sc-7513 / sc-5602. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GAD1 are readily searchable from our website. Different antibodies against the same target such as GAD1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. GAD1 also interacts with the following gene(s): ABAT, GLS, GLUL, RELN, SLC32A1. The following patways have been known to be associated with this gene.