|The GCG gcg (Catalog #MBS2517122) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GCG Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GCG can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).
IHC: 1:25-1:100. Researchers should empirically determine the suitability of the GCG gcg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GCG gcg product has the following accession number(s) (GI #4503945) (NCBI Accession #NP_002045.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GCG Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using GCG Polyclonal Antibody at dilution 1:20)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GCG Polyclonal Antibody at dilution 1:20)
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Immunogen: Synthetic peptide of human GCG. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GCG are readily searchable from our website. Different antibodies against the same target such as GCG may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Diabetes Mellitus, Type 2, Heart Diseases, Hyperglycemia, Hyperinsulinism, Inflammation, Insulin Resistance, Kidney Diseases, Muscular Diseases, Obesity, Vascular Diseases are some of the diseases may be linked to GCG Polyclonal Antibody. Connective Tissue, Embryonic Tissue, Intestine, Liver, Pancreas, Stomach, Uncharacterized Tissue, Uterus tissues are correlated with this protein. GCG also interacts with the following gene(s): FOXA2, GCGR, GIPR, GLP1R, INS, SCT, SST.