anti-GCG antibody product blog
Tags: Antibody; Polyclonal Antibody; GCG; anti-GCG antibody; Glicentin;
The GCG gcg (Catalog #MBS629746) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glicentin (Glucagon) reacts with Human, Porcine, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Glicentin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Frozen, paraffin without proteolytic treatment): 1:50 using the Indirect method. Researchers should empirically determine the suitability of the GCG gcg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GCG gcg product has the following accession number(s) (GI #4503945) (NCBI Accession #NP_002045.1) (Uniprot Accession #P01275). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Glicentin contains the glucagon sequence and is produced in a prominent population of endocrine cells in the distal intestine as well as in pancreatic glucagon cells and in the nerves in the brain. Serum levels of glicentin are elevated after food uptake and in certain clinical conditions, e.g. after resections of the intestine. The functional role of glicentin is largely unknown. Glicentin occurs in endocrine tumors arising in the distal intestine (rectal carcinoids) and in pancreatic islet cell tumors.
Immunogen: Porcine pancreatic Glucagon (BSA) Cellular Localization: Cytoplasm. Positive Control: Pancreas, small intestine. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GCG are readily searchable from our website. Different antibodies against the same target such as GCG may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Diabetes Mellitus, Heart Diseases, Hyperglycemia, Hyperinsulinism, Insulin Resistance, Kidney Diseases, Liver Diseases, Muscular Diseases, Obesity, Vascular Diseases are some of the diseases may be linked to Glicentin (Glucagon). The following patways have been known to be associated with this gene. GCG also interacts with the following gene(s): FOXA2, GCGR, GIPR, GLP1R, GLP2R, SCT. Intestine, Pancreas tissues are correlated with this protein.