|The GDF2 gdf2 (Catalog #MBS2528314) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GDF2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GDF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the GDF2 gdf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GDF2 gdf2 product has the following accession number(s) (GI #7705308) (NCBI Accession #NP_057288.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GDF2 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Mouse heart and liver tissue using GDF2 Polyclonal Antibody at dilution of 1:200)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human ovarian cancer using GDF2 Polyclonal Antibody at dilution of 1:40)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer using GDF2 Polyclonal Antibody at dilution of 1:40)
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia.
Immunogen: Synthetic peptide of human GDF2
Calculated Molecular Weight: 47kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GDF2 are readily searchable from our website. Different antibodies against the same target such as GDF2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Liver tissues are correlated with this protein. The following patways have been known to be associated with this gene. GDF2 also interacts with the following gene(s): ACVRL1, BMPR2, CHAT, ENG, HAMP, HEY1, SMAD5, SMAD9.