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anti-GGCX antibody product blog

Posted on 2015-10-23 07:14:37 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; GGCX; anti-GGCX antibody; Vitamin K-dependent gamma carboxylase;
The GGCX ggcx (Catalog #MBS540794) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GGCX Antibody Affinity Purified reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GGCX can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), IMM, Western Blot (WB).
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500. Researchers should empirically determine the suitability of the GGCX ggcx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The GGCX ggcx product has the following accession number(s) (GI #1220309) (NCBI Accession #AAA91834.1) (Uniprot Accession #P38435). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GGCX Antibody Affinity Purified with the following immunoassay(s):
Western Blot (WB)
Western Blot (WB) GGCX.

Affinity Purified Gamma-glutamic carboxylase Antibody
Mediates the vitamin K-dependent carboxylation of glutatmate residues to calcium-binding gamma-carboxyglutamate residues with the concomitant converstion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.

Immunogen: Synthetic peptide taken within amino acid region 150-200 on human GGCX protein
Expression: Monomer; may interact with CALU. Molecular Function: gamma-glutamyl carboxylase activity; Lyase
Subcellular Location: Endoplasmic Reticulum membrane; Multi-pass membrane protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GGCX are readily searchable from our website. Different antibodies against the same target such as GGCX may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. GGCX also interacts with the following gene(s): GAS6, NQO1, PROC, PROZ. Blood, Bone, Brain, Connective Tissue, Heart, Kidney, Liver, Ovary, Skin, Vascular tissues are correlated with this protein. Blood Coagulation Disorders, Brain Diseases, Congenital Abnormalities, Disease Models, Animal, Liver Diseases, Liver Neoplasms, Nervous System Diseases, Prenatal Exposure Delayed Effects, Pseudoxanthoma Elasticum-Like Disorder with Multiple Coagulation Factor Deficiency, Vascular Diseases are some of the diseases may be linked to GGCX Antibody Affinity Purified.
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