anti-GIPR antibody product blog
Tags: Antibody; Polyclonal Antibody; GIPR; anti-GIPR antibody; gastric inhibitory polypeptide receptor;
The GIPR gipr (Catalog #MBS629451) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Gastric Inhibitory Polypeptide Receptor (GIPR, GIP-R, Glucose-dependent Insulinotropic Polypeptide Receptor) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Gastric Inhibitory Polypeptide Receptor can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500. Researchers should empirically determine the suitability of the GIPR gipr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GIPR gipr product has the following accession number(s) (GI #4503999) (NCBI Accession #NP_000155.1) (Uniprot Accession #P48546). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
GIPR also called glucose-dependent insulinotropic polypeptide, is a 42aa polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
Immunogen: Synthetic peptide selected from the Center region of human GIPR (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GIPR are readily searchable from our website. Different antibodies against the same target such as GIPR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Embryonic Tissue, Intestine, Liver, Pancreas tissues are correlated with this protein. Inflammation, Lung Diseases, Lung Neoplasms are some of the diseases may be linked to Gastric Inhibitory Polypeptide Receptor (GIPR, GIP-R, Glucose-dependent Insulinotropic Polypeptide Receptor). The following patways have been known to be associated with this gene. GIPR also interacts with the following gene(s): GIP.