anti-GJB2 antibody product blog
Tags: Antibody; Polyclonal Antibody; GJB2; anti-GJB2 antibody;
The GJB2 gjb2 (Catalog #MBS153349) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GJB2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s GJB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).GJB2 antibody can be used for detection of GJB2 by Western blot at 1 - 2 mug/ml. Researchers should empirically determine the suitability of the GJB2 gjb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GJB2 gjb2 product has the following accession number(s) (GI #42558283) (NCBI Accession #NP_003995) (Uniprot Accession #P29033). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GJB2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of GJB2 in human colon tissue lysate with GJB2 antibody at (A) 1 and (B) 2 μg/ml.)
The Gap junction beta-2 protein (GJB2), also known as Connexin 26, is member of the gap junction protein family which form structures that were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells (1). Mutations in the GJB2 gene are thought to be responsible for as much as 35-45% of congenital sensorineural hearing loss in some populations (2). Other mutations in this gene have also been linked to a wide array of skin diseases (3).
Conjugate: Unconjugated
Immunogen: GJB2 antibody was raised against a 16 amino acid peptide near the center of human GJB2.
Buffer: GJB2 antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GJB2 are readily searchable from our website. Different antibodies against the same target such as GJB2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Ear, Embryonic Tissue, Eye, Heart, Kidney, Mouth, Skin, Uterus, Vascular tissues are correlated with this protein. Deafness, Disease Models, Animal, Hearing Loss, Sensorineural, Ichthyosis, Keratitis, Keratitis, Ichthyosis, and Deafness (KID) Syndrome, Keratoderma, Palmoplantar, Learning Disorders, Psoriasis, Vohwinkel syndrome are some of the diseases may be linked to GJB2 Antibody. The following patways have been known to be associated with this gene.