|The GJB3 gjb3 (Catalog #MBS2525752) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GJB3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GJB3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the GJB3 gjb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GJB3 gjb3 product has the following accession number(s) (GI #54607056) (NCBI Accession #NP_001005752.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GJB3 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GJB3 Polyclonal Antibody at dilution 1:30)
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
Immunogen: Recombinant protein of human GJB3. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GJB3 are readily searchable from our website. Different antibodies against the same target such as GJB3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. GJB3 also interacts with the following gene(s): GJA1, GJB5, GJC3, KCNQ4, TJP1. The following patways have been known to be associated with this gene. Brain, Eye, Heart, Intestine, Lung, Ovary, Placenta, Skin, Testis, Uterus tissues are correlated with this protein. Cardiovascular Diseases, Deafness, Erythrokeratodermia Variabilis, Erythrokeratodermia, Progressive Symmetric, Hearing Loss, Sensorineural, Hyperkeratosis, Epidermolytic, Lung Neoplasms, Nervous System Diseases, Peripheral Nervous System Diseases, Skin Diseases are some of the diseases may be linked to GJB3 Polyclonal Antibody.