anti-Gjb4 antibody product blog
Tags: Antibody; Polyclonal Antibody; Gjb4; Connexin 30.3; anti-Gjb4 antibody;
The Gjb4 gjb4 (Catalog #MBS6009842) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Connexin 30.3, CT (Gap junction beta-4 protein, Connexin-30.3, Cx30.3, GJB4,) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Connexin 30.3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:50-100. Researchers should empirically determine the suitability of the Gjb4 gjb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Gjb4 gjb4 product has the following accession number(s) (GI #192647) (NCBI Accession #AAA37428.1) (Uniprot Accession #Q02738). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.
Immunogen: Connexin 30.3 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237~266 amino acids from the C-terminal region of human GJB4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Gjb4 are readily searchable from our website. Different antibodies against the same target such as Gjb4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Skin tissues are correlated with this protein. Abnormalities, Multiple, Congenital Abnormalities, Erythrokeratodermia Variabilis, Hyperkeratosis, Epidermolytic, Limb Deformities, Congenital, Musculoskeletal Abnormalities are some of the diseases may be linked to Connexin 30.3, CT (Gap junction beta-4 protein, Connexin-30.3, Cx30.3, GJB4,). The following patways have been known to be associated with this gene.