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anti-GJC2 antibody product blog

Posted on 2018-01-23 10:28:38 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; GJC2; anti-GJC2 antibody;
The GJC2 gjc2 (Catalog #MBS2526245) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GJC2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GJC2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
WB: 1:500-1:2000. Researchers should empirically determine the suitability of the GJC2 gjc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The GJC2 gjc2 product has the following accession number(s) (GI #45439367) (NCBI Accession #NP_065168.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GJC2 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of OP9 cell using GJC2 Polyclonal Antibody at dilution of 1:450)
Western Blot (WB) GJC2.

This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

Immunogen: Synthetic peptide of human GJC2
Calculated Molecular Weight: 47kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GJC2 are readily searchable from our website. Different antibodies against the same target such as GJC2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Eye tissues are correlated with this protein. The following patways have been known to be associated with this gene. Atrophy, Brain Diseases, Leukodystrophy, Hypomyelinating, 2, Neoplasms, Experimental, Nervous System Malformations, Neurodegenerative Diseases, Spastic Paraplegia 44, Autosomal Recessive are some of the diseases may be linked to GJC2 Polyclonal Antibody. GJC2 also interacts with the following gene(s): AIMP1, FA2H, KIAA0415, PLP1, SPG11, SPG21.
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