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anti-GLUT-1 antibody product blog

Posted on 2015-09-03 20:16:07 by mybiosource_staff
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Tags: Antibody; GLUT-1; Polyclonal Antibody; anti-GLUT-1 antibody;
The GLUT-1 slc2a1 (Catalog #MBS224216) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI HUMAN GLUT-1 (C-TERMINAL) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GLUT-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB).
Western Blot: This item detects a band of approximately 54kDa in human Jurkat cell lysates.
Immunohistology - Paraffin: Minimum Dilution: 1;100; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Western Blotting: Minimum Dilution: 1:500; Maximum Dilution: 1:2000. Researchers should empirically determine the suitability of the GLUT-1 slc2a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The GLUT-1 slc2a1 product has the following accession number(s) (GI #165377226) (NCBI Accession #NP_035530.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

MBS224216 specifically recognises an epitope within the C-Terminal (CT) region of GLUT-1 (Glucose transporter 1), an ubiquitously expressed integral membrane glycoprotein, and member of the major facilitator superfamily, which plays a major role in the transport of glucose across the cell membrane, and the blood-brain barrier.

GLUT-1 slc2a1

Perservative Stabilisers: 0.1% Sodium Azide (NaN3). Immunogen: Keyhole limpet haemocyanin conjugated synthetic peptide sequence C-ELFHPLGADSQV from the C-terminal region of GLUT-1 (NM_006516).
Histology Positive Control Tissue: Colorectal carcinoma
Buffer Solution: Phosphate buffered saline
Antiserum Preparation: Antiserum to human GLUT-1 (CT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Target Species: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GLUT-1 are readily searchable from our website. Different antibodies against the same target such as GLUT-1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Connective Tissue, Embryonic Tissue, Eye, Kidney, Liver, Lung, Ovary, Pancreas tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Diabetes Mellitus, Type 2, Disease Models, Animal, Heart Diseases, Kidney Diseases, Liver Diseases, Liver Neoplasms, Necrosis, Seizures are some of the diseases may be linked to RABBIT ANTI HUMAN GLUT-1 (C-TERMINAL). The following patways have been known to be associated with this gene.
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