anti-GM2A antibody product blog
Tags: Antibody; Polyclonal Antibody; GM2A; anti-GM2A antibody;
The GM2A gm2a (Catalog #MBS247816) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GM2A reacts with Gibbon, Gorilla, Human and may cross-react with other species as described in the data sheet. MyBioSource\'s GM2A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).IHC-P (10 - 12.5 ug/ml). Researchers should empirically determine the suitability of the GM2A gm2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GM2A gm2a product has the following accession number(s) (GI #39995109) (NCBI Accession #NP_000396.2) (Uniprot Accession #P17900). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human GM2A with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-GM2A antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) (Anti-GM2A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
The protein encoded by this gene is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme, beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease.
Target Species: Human
Immunogen Description: Synthetic 14 amino acid peptide from N-terminus of human GM2A. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (86%). Immunogen Type: Synthetic peptide
Immunogen: GM2A antibody was raised against synthetic 14 amino acid peptide from N-terminus of human GM2A. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (86%).
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GM2A are readily searchable from our website. Different antibodies against the same target such as GM2A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.