|The GPR3 gpr3 (Catalog #MBS247444) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GPR3 reacts with Gibbon, Gorilla, Hamster, Human, Monkey, Mouse, Rat
Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s GPR3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (6 ug/ml). Researchers should empirically determine the suitability of the GPR3 gpr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GPR3 gpr3 product has the following accession number(s) (GI #4885325) (NCBI Accession #NP_005272.1) (Uniprot Accession #P46089). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human GPR3 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-GPR3 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) (Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging (Ledent et al. 2005).
Target Species: Human
Immunogen Description: Synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%); Rabbit (93%); Bovine, Panda, Pig (80%). Immunogen Type: Synthetic peptide
Immunogen: GPR3 antibody was raised against synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%); Rabbit (93%); Bovine, Panda, Pig (80%).
Antigen Modification: Extracellular Domain. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GPR3 are readily searchable from our website. Different antibodies against the same target such as GPR3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.