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anti-GPR37 antibody product blog

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Posted on 2018-01-12 22:59:28 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; PAEL Receptor / GPR37; anti-GPR37 antibody; GPR37;
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The GPR37 gpr37 (Catalog #MBS244849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human PAEL Receptor / GPR37 reacts with Human
Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s PAEL Receptor / GPR37 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (6 - 11 ug/ml). Researchers should empirically determine the suitability of the GPR37 gpr37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The GPR37 gpr37 product has the following accession number(s) (GI #4885323) (NCBI Accession #NP_005293.1) (Uniprot Accession #O15354). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human PAEL Receptor / GPR37 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) GPR37.

Immunohistochemistry (IHC) (Anti-PAEL Receptor / GPR37 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) GPR37.

Immunohistochemistry (IHC) (Anti-GPR37 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) GPR37.

Immunohistochemistry (IHC) (Anti-PAEL Receptor / GPR37 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) GPR37.

Immunohistochemistry (IHC) (Anti-PAEL Receptor / GPR37 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) GPR37.

GPR37 is an Orphan-A GPCR with an unknown ligand. GPR37 was recently identified as the PAEL receptor, a Parkin substrate involved in autosomal recessive juvenile Parkinson\'s (PDJ) disease. The PAEL receptor becomes unfolded, insoluble, and ubiquitinated when overexpressed, leading to unfolded protein-induced cell death. When the PAEL receptor is ubiquitinated by Parkin, it gets degraded, resulting in the suppression of cell death.

Target Species: Human
Immunogen Description: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human GPR37. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (95%); Marmoset (90%); Rabbit (85%); Panda (80%). Immunogen Type: Synthetic peptide
Immunogen: PAEL Receptor / GPR37 antibody was raised against synthetic 20 amino acid peptide from N-terminal extracellular domain of human GPR37. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (95%); Marmoset (90%); Rabbit (85%); Panda (80%).
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GPR37 are readily searchable from our website. Different antibodies against the same target such as GPR37 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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