|The GPX1 gpx1 (Catalog #MBS220030) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s GLUTATHIONE PEROXIDASE can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).
ELISA: Minimum Dilution: 1/100; Maximum Dilution: 1/250. Researchers should empirically determine the suitability of the GPX1 gpx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GPX1 gpx1 product has the following accession number(s) (GI #27806591) (NCBI Accession #NP_776501.1) (Uniprot Accession #P00435). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Sheep anti Bovine glutathione peroxidase antibody detects human glutathione peroxidise (GSH-Px), a selenium-containing tetrameric enzyme found in mammalian erythrocytes. GSH-Px has an important role in protecting cellular and subcellular membranes from oxidative damage, and functions to detoxify peroxide though the reduction of hydrogen peroxide and organic peroxides. An increase in GSH-Px in tumour cells may be associated with resistance to drugs that act by generating reactive oxygen species, for example doxorubicin.
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin. Immunogen: Glutathione peroxidase from bovine erythrocytes.
Buffer Solution: Phosphate buffered saline
Antiserum Preparation: Antisera to bovine glutathione peroxidase were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.
Target Species: Bovine. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GPX1 are readily searchable from our website. Different antibodies against the same target such as GPX1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Intestine, Kidney, Lens, Liver, Lung, Muscle, Ovary, Pancreas, Testis tissues are correlated with this protein. GPX1 also interacts with the following gene(s): GSS, GSTA2, GSTA4, GSTM2, GSTP1, GSTT1, TXNRD1. Atherosclerosis, Breast Neoplasms, Cardiovascular Diseases, Heart Diseases, Hyperglycemia, Inflammation, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Necrosis are some of the diseases may be linked to SHEEP ANTI BOVINE GLUTATHIONE PEROXIDASE:Alk. Phos.