anti-GREM1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-GREM1 antibody; GREM1;
The GREM1 grem1 (Catalog #MBS2520379) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GREM1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GREM1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).WB: 1:500-1:2000. Researchers should empirically determine the suitability of the GREM1 grem1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GREM1 grem1 product has the following accession number(s) (GI #300797328) (NCBI Accession #BC069525) (Uniprot Accession #O60565). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GREM1 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Mouse testis tissue using GREM1 Polyclonal Antibody at dilution of 1:700)
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen: Recombinant protein of human GREM1
Calculated MW: 21kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GREM1 are readily searchable from our website. Different antibodies against the same target such as GREM1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Brain, Connective Tissue, Embryonic Tissue, Heart, Kidney, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.