anti-Gria1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-GRIA1 antibody; GRIA1; GluR1;
The Gria1 gria1 (Catalog #MBS220876) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI RAT GLUTAMATE RECEPTOR 1 (C-TERMINAL) reacts with Hamster, Human, Monkey and may cross-react with other species as described in the data sheet. MyBioSource\'s GluR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB).Western Blot: Western blot analysis of rat brain shows a single band of approximately 110 kDa co-migrating with GluR1 expressed in transfected cells.
Immunohistology: Paraformaldehyde or paraformaldehyde/glutaraldehyde are suitable. Cryostat and vibratome sections can be used with or without Triton X-100 treatment.
Immunohistology - Frozen: Minimum Dilution: 1 ug/ml; Maximum Dilution: 3 ug/ml
Western Blotting: Minimum Dilution: 0.5 ug/ml; Maximum Dilution: 2.5 ug/ml. Researchers should empirically determine the suitability of the Gria1 gria1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Gria1 gria1 product has the following accession number(s) (GI #29789269) (NCBI Accession #NP_113796.1) (Uniprot Accession #P19490). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
S-H-S-S-G- M-P-L-G-A- T-G-L.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
MBS220876 recognises the glutamate receptor 1 (also known as AMPA) which acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.This antibody linked to immobilized Protein An immunoprecipitates detergent-solubilized receptor from brain or transfected cells.
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
Preparation: Purified Ig prepared by affinity chromatography. Immunogen: Synthetic peptide corresponding to the C terminal region of the native molecule conjugated to Bovine Serum Albumin.
Buffer Solution: Phosphate buffered saline
Target Species: Rat. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Gria1 are readily searchable from our website. Different antibodies against the same target such as Gria1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Heart tissues are correlated with this protein. The following patways have been known to be associated with this gene.